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ANTI - ds DNA ANTIBODY SERUM
Sample: Blood
Using a sequential approach, this study established that DNA-ELISA could be used to detect and quantify anti-dsDNA Abs with moderately high sensitivity (77.3% of SLE patients), but with a low specificity (42.4% of all clinical conditions).
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In the evaluation of someone with lupus nephritis, a high level (titer) of anti-dsDNA is generally associated with ongoing inflammation and damage to the kidneys. A very low level of anti-dsDNA is considered negative but does not exclude a diagnosis of lupus. Only about 65-85% of those with lupus will have anti-dsDNA.
In the evaluation of someone with lupus nephritis, a high level (titer) of anti-dsDNA is generally associated with ongoing inflammation and damage to the kidneys. A very low level of anti-dsDNA is considered negative but does not exclude a diagnosis of lupus. Only about 65-85% of those with lupus will have anti-dsDNA.
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